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History
of Anaesthesia
History
of Anesthesia
Dental
Anesthesia History
Anesthesia
Administration Story
Evolution of
Anesthesia
History
of Surgery
Surgery without
Anesthesia
Anesthesia
Anesthesia
Discovery
Ether
Anesthesia
Discovery of
Anesthesia
Surgery/
Anesthesia
Chloroform
Anesthesia
Vintage General
Anesthesia
Anesthesia
in 1950s
Anesthesia
1940
Anaesthesia
Ether Anesthetic
Introduction to
Anesthesia
Stages of Anesthesia
Vintage Images
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How Does Anesthesia Work?
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Administering low-dose intravenous ketamine transforms multimodal general anesthesia by targeting central pain pathways before surgical stimulation begins. Ketamine functions as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, dampening dorsal horn wind-up and preventing acute central sensitization (Peltoniemi et al., 2016). When combined synergistically with gamma-aminobutyric acid (GABA) receptor agonists like propofol, it produces reliable hypnotic depth and somatic analgesia
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