A change in one gene can disrupt thousands of others in HD. A study in pigs suggests an explanation: expanded huntingtin ...

In plain language. Written by scientists. Scientists discovered that a specific type of brain cell becomes unusually quiet in Huntington’s disease. By restoring the activity of these cells in mice, ...

In plain language. Written by scientists. The SIGNAL study did not meet its key clinical goals for #HuntingtonsDisease to slow or improve HD symptoms, but the results are still informative for the HD ...

In plain language. Written by scientists. Getting “stuck” on a thought, action, or conversation can be a symptom of HD—not stubbornness. New research suggests perseveration may begin earlier than ...

In plain language. Written by scientists. As promised, HDBuzz's Jeff Carroll finally signed up for the Enroll-HD study. Learn more about this important global HD "observational study" here.

Most of us know what it’s like to have something stuck in our minds. A catchy song. A favourite YouTube video you watch again. A conversation that keeps circling in your mind. Usually, our brains move ...

Prana Biotech has announced a phase 2 clinical trialclinical trial Very carefully planned experiments designed to answer specific questions about how a drug affects human beings in Huntington’s ...

Gene silencing drug injected into spinal fluid in ALS patients proves safe. Good news for similar planned HD trials.

In plain language. Written by scientists. September brought progress across the HD research landscape. From brain waves and visual thinking to DNA repeats, nutrition, inclusive care, new technologies, ...