Recording the spiking activity of muscle fibers at high resolution in awake, behaving mice, reveals that locomotor speed is driven by highly variable subsets of motor units.

Learn more about eLife assessments The distribution of synaptic and extra-synaptic AMPA receptors (AMPARs) on neuronal plasma membranes is correlated with learning and memory. Although AMPAR ...

This valuable study substantially improves the phylogenetic framework for Kinetoplastea through greatly expanded sampling of free-living neobodonids; the phylogenomic analyses provide convincing ...

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest ...

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up ...

eLife reviews plant biology research including development, epigenetics, genomics, signalling, metabolism and plant-microbe interactions. Learn more about what we review and sign up for the latest ...

New funding, awards for metadata and UX excellence, and outstanding research articles are among the highlights of the past year at eLife. Last week, Wellcome announced a £2.4m investment in eLife ...

eLife now encourages authors to include a Key Resources Table in the Materials and Methods section of their papers. In the view of Norbert Perrimon, “Journals have a unique opportunity to have a huge ...

Inner ear cochlear spiral ganglion neurons (SGNs) transmit sound information to the brainstem. Recent single cell RNA-Seq studies have revealed heterogeneities within SGNs. Nonetheless, much remains ...

eLife has changed its editorial process to eliminate accept/reject decisions after peer review and instead provide readers with richer and more nuanced assessments of articles. eLife changed its ...

Analysis of knockout and knockdown melanoma cells and TCGA melanoma data shows that the microphthalmia-associated transcription factor (MITF) is a major repressor of extracellular matrix (ECM) and ...

Crystal structures of γ-protocadherin cell-cell recognition dimers reveal the determinants of clustered protocadherin homophilic specificity and cis interaction region structures alongside mutagenesis ...