A generic version of a breakthrough cystic fibrosis drug, manufactured in Bangladesh for a fraction of the American price, may give some families around the world an unlikely lifeline. Josua Lottering ...

Two existing types of drugs synergize to improve the clearing of mucus from the lungs of animals with cystic fibrosis, a Stanford Medicine research team has found. “I really hope this discovery can ...

Findings from a phase 1 trial showed no adverse effects higher than grade 3 among those who received ruxolitinib/abemaciclib for advanced myelofibrosis. Combining ...

As we age, we don’t recover from injury or illness like we did when we were young. But new research from UC San Francisco has found gene regulators that turn genes on and off that could restore the ...

INCA033989 shows potential in treating myelofibrosis, with significant spleen volume reduction, anemia response, and symptom improvement in phase 1 studies. The investigational therapy demonstrates ...

Bone marrow biopsy is conducted to perform a morphologic examination of the bone marrow and to look for the presence of characteristic “hairy” cells and infiltrate with increased reticulin. There may ...

Robert Silvers is an assistant professor in the Department of Chemistry and Biochemistry. A research team at Florida State University’s Institute of Molecular Biophysics and Department of Chemistry ...

Liver fibrosis may be diagnosed and staged — no fibrosis (stage F0), mild fibrosis (F1), significant fibrosis (F2), advanced fibrosis (F3), and cirrhosis (F4) — with the use of clinical parameters and ...

The scientific imperative to identify drugs that could repair mutant CFTR presented a formidable challenge. Small molecules that specifically bound and repaired a defective CFTR peptide fold were ...