A new theoretical framework proposes that early adversity alters the developing biological architecture through which later ...
Exeliris Co. Ltd. and Lin Gang Laboratory have identified new glutamate receptor ionotropic, NMDA 2B (GRIN2B; GluN2B) and serotonin transporter (SERT) inhibitors reported to be useful for the ...
原标题:潘孝敬、柳峰、黄恺联合团队首次解析蚊子离子型受体(ionotropic receptors)的配体识别与门控机制 ...
Cryo-electron microscopy structures of the Anopheles stephensi IR8a-IR75k receptor complex reveal how carboxylic acid ...
Neurotransmitter receptors and ligands play a fundamental role in chemical signaling throughout the nervous system by controlling how messages are received and processed by neurons. Direct signaling ...
美国布兰代斯大学Sengupta, Piali团队开发出肠神经元嗜离子受体调节盐胁迫抗性。2026年4月1日出版的《自然》杂志发表了这项成果。 在这里,该研究组发现I3咽肠神经元通过I3特异性的嗜离子受体 ...
Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin analogues that promote glucose-mediated insulin release and are used to treat type 2 diabetes mellitus and obesity. GLP-1 receptor ...
In the brains of newborn mammals, the rapid, experience-dependent GluN2B-to-GluN2A subunit switch in synaptic NMDA receptors drives synaptic maturation and enables proper cognitive development.