Synapses in the hippocampus dwindle with age. Might a little-known, lipid-cleaving enzyme keep them from withering away? In the October 15 Nature Neuroscience, scientists led by Amar Sahay at Harvard ...
When it comes to new brain anatomy, clearance pathways seem to be the gift that keeps on giving. In a preprint posted September 27 on bioRxiv, scientists led by David Attwell at University College ...
Digging deeper into the genetic causes of Alzheimer’s disease, some scientists are studying epigenetic regulation. In the October 12 Nature Aging, a group led by Jinying Zhao at the University of ...
In the latest development on diagnostic methods for Alzheimer’s disease going mainstream, the U.S. Food and Drug Administration approved clinical use of Lantheus’ tau PET tracer florquinitau, aka ...
In the latest development on diagnostic methods for Alzheimer’s disease going mainstream, the U.S. Food and Drug Administration approved clinical use of Lantheus’ tau PET tracer florquinitau, aka ...
Two groups of scientists have found that the same protein can have opposing effects on α-synuclein pathology. Microglia eliminate α-synuclein from neurons by “trogocytosis.” Silencing the glycoprotein ...
Also the 24th Alzheimer's Disease and Related Disorders Annual convention of the Dementia Society of the Philippines ...
03 December 2026 DOWNLOAD TO YOUR CALENDAR Dublin, Ireland View Conference Website ...
Anti-amyloid immunotherapies come with a risk of serious brain hemorrhage, which can be mitigated via monitoring for amyloid-related imaging abnormalities (ARIA) via MRI scans. Early signs of edema ...
Scientists sorely need biomarkers of TDP-43 pathology, but finding reliable ones has been difficult. Now, two groups, working independently, have proposed a new angle—cryptic circular RNAs, or ...
The tau locus comes in two major genetic configurations, the H1 and H2 haplotypes. The latter carries a stretch of DNA, including the tau gene, that is flipped in orientation. As it turns out, a ...
Ask a clinician or a researcher about the blood-brain barrier (BBB) in Alzheimer’s disease, and you may hear about amyloid or leaky tight junctions. Fibronectin, a major scaffold protein, won’t ...
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