Learn more about eLife assessments The distribution of synaptic and extra-synaptic AMPA receptors (AMPARs) on neuronal plasma membranes is correlated with learning and memory. Although AMPAR ...

This valuable study substantially improves the phylogenetic framework for Kinetoplastea through greatly expanded sampling of free-living neobodonids; the phylogenomic analyses provide convincing ...

In this episode, we explore how male gorillas trade size for sperm production, how fever changes the stickiness of malaria-infected cells, the neuroscience behind gambling machines, whether babies are ...

New funding, awards for metadata and UX excellence, and outstanding research articles are among the highlights of the past year at eLife. Last week, Wellcome announced a £2.4m investment in eLife ...

This study presents a valuable finding on whether executive resources mediate the impact of language predictability in reading in the context of aging. The evidence is solid in the investigation of ...

In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...

Bacterial exonuclease III exhibits underestimated enzymatic activities on single-stranded DNA, which may redefine its roles in relevant biological processes and biosensor development.

This important study explores the interplay between Legionella Dot/Icm effectors that modulate ubiquitination of the host GTPase Rab10, which undergoes phosphoribosyl-ubiquitination by the SidE family ...

This manuscript addresses an important question and provides some clear instructions on the use of the λ chain locus. In particular, it highlights the role of Kidins220 in extending B cell survival so ...

This study presents valuable findings on the changes in immune cell populations and stromal cells occurring at the CNS borders in a neonatal bacterial meningitis model, focusing on fibroblasts, ...

Reactive oxygen species (ROS) accumulation is a cardinal feature of skeletal muscle atrophy. ROS refers to a collection of radical molecules whose cellular signals are vast, and it is unclear which ...

School of Life Sciences, IDG/McGovern Institute for Brain Research, MOE Key Laboratory of Protein Sciences, Tsinghua University, China; Tsinghua-Peking Center for Life Sciences, China; ...