The regulatory landscape for MM has undergone substantial transformation, with multiple novel therapeutic agents receiving US Food and Drug Administration approval within the preceding few years based ...

Multiple myeloma is a type of blood cancer that starts in your bone marrow. This is the soft, spongy tissue inside your bones that makes most of your blood cells. It includes plasma cells, which help ...

This ASCO Living Guideline is reviewed on an eight-week cycle. Please see the online dynamic version for the latest updates. ASCO Guidelines provide recommendations ...

Multiple myeloma is considered to be relapsed if symptoms of the disease appear after a time of improvement. It’s considered to be refractory when it gets worse even though it’s being treated. To ...

Early stage multiple myeloma is often asymptomatic, and early symptoms can be subtle and easy to miss. Delayed diagnosis and treatment may affect survival. Possible early symptoms include bone pain, ...

Lindsay Curtis is a health & medical writer in South Florida. She worked as a communications professional for health nonprofits and the University of Toronto’s Faculty of Medicine and Faculty of ...

Serum Free Light Chain Measurement Aids the Diagnosis of Myeloma Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays ...

Histopathological image of multiple myoloma. Smear preparation of bone marrow aspirate stained with May-Grünwald-Giemsa procedure. It doest not represent a histopathologic image but essentially helps ...

Gagandeep Brar, MD, is a board-certified hematologist and medical oncologist. Her research interest is in gastrointestinal malignancies with a focus on immune and targeted therapies. Smoldering ...

Multiple myeloma starts with genetic changes in plasma cells, which are not inherited but occur spontaneously. The condition progresses from monoclonal gammopathy of undetermined significance (MGUS) ...