A new research paper was published on the cover of Aging, titled, "Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell ...

Deep inside the neurons of an aging brain, mitochondria are quietly failing. These organelles, which supply the enormous ...

The loss of muscle tissue—referred to as muscle atrophy in medical terms—can occur as a result of lack of physical activity for an extended period of time; aging; alcohol-associated myopathy—a pain ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

A review of preclinical evidence finds that nanomaterials can improve mitochondrial targeting, organelle protection and ...

“[...] our current work has provided a novel strategy to enrich for a sub-population of cancer cells, with high basal levels of mitophagy.” Mitophagy is a ...

Autophagy is a natural, conserved process where cells degrade and recycle their own components, including damaged proteins and organelles. This targeted removal is orchestrated by cargo receptors, ...

"Our new tool allows us to study how changes in mitochondrial abundance and the mitochondrial genome affect cells and organisms," said Jun Wu, Ph.D., Associate Professor of Molecular Biology at UT ...

Autophagy is a process used by cells as a recycling system to transport and break down organelles and other cytosolic components, which become enveloped in a membrane called the autophagosome. When ...