Clinical Trials Arena on MSN

Alnylam reports preliminary Phase Ib trial results for brezosiran

The trial is designed to assess intrathecal doses of brezosiran in adults aged 25 to 70 years with genetically confirmed HD.
Medscape

A Man’s Rare Late Complication After Brain Tumor Therapy

Long after successful radiotherapy for pineal germinoma, this patient developed pituitary insufficiency and later a rare metachronous CNS germ cell tumor.
BioSpace

RYBREVANT FASPRO™ (amivantamab and hyaluronidase-lpuj) combination demonstrates 77% overall response rate in first-line treatment of patients with adva…

Responses were deep and durable, with 65% ongoing at clinical cutoff; Results support continued evaluation of the ...
BIOENGINEER

When the Injured Brain Fights the Ventilator: Review Maps Neurogenic Breathing Asynchrony

A review in Neurocritical Care describes how neurogenic breathing patterns in acutely injured brain patients cause ...
Stock Titan

Solid Biosciences Announces European Commission Orphan Designation for SGT-212 and Continued Progress in the FALCON Trial in Friedreich’s Ataxia

Five participants received SGT-212 in the Phase 1b FALCON trial; initial data are expected in Q1 2027. FDA granted three ...