A new discovery by neuroscientists at Brown University's Carney Institute for Brain Science challenges long-held beliefs in neurobiology about how neurons extend axons to reach their targets.

Effective axon regeneration is critical for restoring nerve function in patients with axon injury-related neurological diseases, yet adult mammals show limited regenerative capacity in central axonal ...

The ultrathin tendrils that zip messages around the nervous system are often drawn as smooth lines. But a new study adds some flourishes to that classical picture. Like a garland of cranberries hung ...

DZNE researchers have uncovered a mechanism that determines why a neuron usually forms a single, long extension called an "axon"—a phenomenon that is fundamental to how our brain functions. Contrary ...

To allow for the local translation of proteins that suit the ever-changing needs of the axon, neurons must ship transcripts from the soma to their outermost reaches. For thousands of these mRNAs, ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS). The study, ...

Axons are the brain’s information highways, transporting cellular cargo, chemical signals, and electrical impulses to other cells. These “roads” are typically depicted as smooth and cylindrical, with ...

Much like tree branches, hundreds of axons extend from neurons during development. These axons serve as information highways that enable neurons to communicate with different cells across the body.

New research in adult zebrafish shows that transient dendritic pruning driven by repressed mTORC1 signaling is essential for efficient axonal regeneration, challenging growth-promotion strategies in ...