Target ALS is proud to announce that three consortia have been selected for awards through our Biomarker Consortia Program. As new therapeutics begin moving the needle for people with ALS, the field ...

ALS is an irreversible degenerative disease of motor neurons, which are the nerve cells in the spinal cord and brain that control muscles. While most people’s minds remain acute, ALS hinders all of ...

The numbers behind ALS tell a powerful story, illuminating the urgent need for progress in combating this life-altering disease. With each new study, researchers uncover vital information about risk ...

Fasciculations, or involuntary muscle twitches, happen to about 70% of people. While it’s typically benign, the condition can become a cause for concern when it starts happening frequently.

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurological disease primarily affecting motor neurons. Over time, these motor neurons deteriorate and die, leading to muscle weakness, loss of ...

Brain and spinal cord donation is one of the most meaningful gifts a person with ALS, or their loved ones, can offer. These donations give scientists something they simply cannot see through scans, ...

Lab director and Professor in the EPFL Brain Mind Institute Brian McCabe’s quest began with a simple yet profound question: What role does TDP-43 dysfunction play in ALS? The protein is aggregated and ...

Today, we mourn the loss of Brooke Eby. Brooke was a powerhouse. Witty, clever, joyful, and direct. She was unwilling to be silenced by ALS. To take a fatal diagnosis at 33 and find humor in it, and ...

At least 70 different drugs have been tested in clinical trials completed or on-going. Many of these treatments aim to dampen disease factors that arise after motor neuron degeneration has been ...

Dr. Yini Li never expected to find herself in the world of neurodegenerative disease. As a PhD student captivated by the elegance of RNA modifications and epigenetic regulation, she was drawn to the ...

When Dr. Stella Sarraf first asked if anyone looked at the retina to detect ALS, the answer was simple: no one knew. That question sparked a research journey that may change how we diagnose and screen ...