Chemical synapses transmit information within the nervous system. When a presynaptic cell is electrically excited, synaptic vesicles fuse with the presynaptic membrane causing messenger substances ...

It takes just a few milliseconds: A vesicle, only a few nanometers in size and filled with neurotransmitters, approaches a cell membrane, fuses with it, and releases its chemical messengers into the ...

Synaptic transmission forms the fundamental process through which neurons communicate across the central and peripheral nervous systems. This complex biological mechanism takes place at the synapse, ...

A new review proposes that stress-induced overactivation of phospholipase A2 deposits toxic lysophospholipids directly at ...

Discover the latest articles and news in related subjects. Figure 2: l-AP5 (250 μM) completely inhibited NMDAR-mediated synaptic responses at silent synapses but lost effectiveness after pairing.

A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...

A sweeping review reveals how dormant silent synapses are activated through coordinated molecular machinery, and how their ...

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies (CAPS) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

(1) A nerve impulse arrives. (2) This causes calcium ion channels to open, resulting in an influx of calcium ions in the terminal. (3) This causes synaptic vesicles to fuse with the terminal membrane, ...

Neurotransmission, or synaptic transmission, corresponds to the movement of signals between neurons, permitting the transmission of information through the proliferation of action potentials. This ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...