Single-stranded or double-stranded DNA junctions with recessed 5′ ends serve as loading sites for the checkpoint clamp, 9-1-1, which mediates activation of the apical checkpoint kinase, ATRMec1.
The DNA polymerase III holoenzyme, which carries out chromosomal DNA replication in Escherichia coli, comprises three main parts: the catalytic core, responsible for DNA synthesis; the doughnut-shaped ...
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