Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Deep inside the brain, a tiny antenna on each neuron may determine how gracefully the body ages. A new study reports that ...
Noboru Mizushima is a cell biologist who has studied the molecular mechanisms and in vivo roles of autophagy, a process by which cells degrade their own cytoplasmic components. He is currently a ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
A rigorous new review finds that the BAG3-HSP70 autophagy axis is prognostically relevant and pharmacologically tractable in ...
HHS unveiled a new Alzheimer's and dementia plan in Fort Lauderdale focused on prevention and early detection. Here is what is promised and proven. Final CDC Data Put U.S. Fertility Rate at Record Low ...
In a landmark biomedical breakthrough that challenges decades of conventional cell biology, an international team of researchers has demonstrated that autophagy—the body's internal cellular ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson's disease protein
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
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