LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...

As a researcher, I still remember the discomfort I felt every time I had to sacrifice laboratory animals for an experiment. For decades, animals like mice, rats and pigs have been essential tools in ...

A fundamental challenge in preclinical research is accurately predicting human responses using conventional animal models. Traditional approaches often fail to adequately model human disease, creating ...

Cells are the smallest unit of life and the building blocks for all organisms. Each component of a cell has its own function. Animal and plant cells differ and they have similarities. Nucleus, cell ...

Animals, from worms and sponges to jellyfish and whales, contain anywhere from a few thousand to tens of trillions of nearly genetically identical cells. Depending on the organism, these cells arrange ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

The team observed the emergence of the three-dimensional embryo-like structures under a microscope in the lab. These started producing blood (seen here in red) after around two weeks of development - ...