Patients with Alzheimer's disease (AD) have lower levels of the neuromodulator acetylcholine (ACh) in their brains. Donepezil, an AD drug, increases brain ACh levels and improves AD-associated ...

New evidence in the April 5, 2006 Cell Metabolism reveals a molecular mechanism that may play a general role in animals' ability to respond appropriately when starved. The researchers discovered a ...

Clinically approved drugs induced ChAT expression and acetylcholine production in podocytes in vivo, suggesting the pathway could be pharmacologically targeted.

ELECTRICAL stimulation of a peripheral sensory nerve produces an increase in the rate at which acetylcholine (ACh) is liberated from the surface of the exposed contralateral somatosensory cortex 1.

Research led by Peking University, China, has discovered a single type of retinal photoreceptor cell in Drosophila (fruit fly) is involved in both visual perception and circadian photoentrainment by ...

The Nature Index 2026 Research Leaders reveal the leading institutions and countries/territories in the natural sciences, health sciences, applied sciences and social sciences, according to their ...

Share on Pinterest Researchers say circuits in the brain could help provide pain relief without the use of opioids. Westend61/Getty Images Researchers have identified an alternative pain control ...

A recent study posted to the bioRxiv* preprint server assessed the mechanism by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron and Alpha variants of concern (VOCs) inhibit ...